Modibo Maiga and Mohamed Diame have been recalled to the West Ham United starting XI after making substitute appearances against Chelsea last weekend.
Long-term absentee Andy Carroll is not expected to return to training until next week, but the Hammers are otherwise at full strength.
Darren Bent will spearhead the Fulham attack as star striker Dimitar Berbatov misses out following a bout of illness.
The versatile Kieran Richardson will provide support at the back in the absence of Brede Hangeland, who is sidelined with a nerve problem.
West Ham: Jaaskelainen; Demel, Tomkins, Collins, McCartney; Jarvis, Diame, Noble, Downing; Nolan; Maiga
Fulham: Stekelenburg; Zverotic, Hughes, Amorebieta, Richardson; Duff, Sidwell, Parker, Kasami; Taarabt; Bent