Adelaide Crows head coach Phil Walsh has been stabbed to death at his home, South Australia Police have confirmed.

The police were called to a domestic dispute in the early hours of Friday, and after being treated for knife injuries, Walsh died at the scene.

Walsh's 26-year-old son has been charged with murder, while his wife was taken to hospital with non-life threatening injuries.

"There's been an argument, I can't tell you anything about the argument," a South Australia detective told reporters. "But as a result of that both Mr Walsh and his wife received a wound and the wound ultimately caused Mr Walsh's death."

Walsh was named Adelaide coach in October 2014.