England have selected Teimana Harrison at openside flanker as they aim to complete a series whitewash over Australia on Saturday.
The 23-year-old Northampton Saints man, who made his debut against Wales in May, replaces the injured James Haskell at Sydney's Allianz Stadium.
Eddie Jones leaves the remainder of his side unchanged, with wing Jack Nowell fit to start after passing concussion protocols.
England beat the Wallabies in both Brisbane and Melbourne to secure their first ever series win Down Under.