England head coach Stuart Lancaster has placed Joe Marler in the new-look front row for Saturday's clash against Argentina.
Marler will line up at Twickenham alongside Dylan Hartley and David Wilson, who replace Tom Youngs and Dan Cole, while Mako Vunipola has also lost his starting spot.
"Joe Marler was excellent off the bench against Australia and merits his opportunity, as does David Wilson, who has been pushing hard for selection," said Lancaster.
"Dylan gets a deserved chance at hooker with Tom Youngs on the bench after the safe arrival of his first child this morning. Rob Webber remains on standby."
Christian Wade and Marlon Yarde failed late fitness tests.
England team: 5 Mike Brown (Harlequins, 19 caps), 14 Chris Ashton (Saracens, 35 caps), 13 Joel Tomkins (Saracens, 1 cap), 12 Billy Twelvetrees (Gloucester Rugby, 6 caps), 11 Ben Foden (Northampton Saints, 32 caps), 10 Owen Farrell (Saracens, 17 caps), 9 Lee Dickson (Northampton Saints, 10 caps), 1 Joe Marler (Harlequins, 13 caps), 2 Dylan Hartley (Northampton Saints, 48 caps), 3 David Wilson (Bath Rugby, 29 caps), 4 Joe Launchbury (London Wasps, 12 caps), 5 Courtney Lawes (Northampton Saints, 23 caps), 6 Tom Wood (Northampton Saints, 21 caps), 7 Chris Robshaw (Harlequins, capt, 18 caps), 8 Billy Vunipola (Saracens, 3 caps)
Replacements: 16 Tom Youngs (Leicester Tigers, 10 caps), 17 Alex Corbisiero (Northampton Saints, 18 caps), 18 Dan Cole (Leicester Tigers, 41 caps), 19 Geoff Parling (Leicester Tigers, 17 caps), 20 Ben Morgan (Gloucester Rugby, 13 caps), 21 Ben Youngs (Leicester Tigers, 34 caps), 22 Toby Flood (Leicester Tigers, 58 caps), 23 Alex Goode (Saracens, 11 caps)
