Scrum-half Sebastien Tillous-Borde has been ruled out of France's opening Six Nations clash with Scotland after failing to recover from a knee injury picked up while on club duty with Toulon last weekend.
The 29-year-old started all three of France's November Tests alongside fly-half Camille Lopez, but has not been named in coach Philippe Saint-Andre's 31-man squad for the clash in Paris on Saturday.
France will also be missing Toulouse number eight Louis Picamoles, though Racing Metro full-back Brice Dulin earns a recall.
Tillous-Borde has won 11 caps for France since making his debut in 2008.
