Former South Africa hooker Gary Botha leads a four-strong list of players that will depart Toulouse at the end of the season.
The ex-Harlequins hooker will play his last game for the club against Grenoble this weekend, while Luke Burgess, Yannick Jauzion and Jean-Baptiste Poux will also depart in the summer.
Botha leaves despite having one year remaining on his contact, but former France international Jauzion is retiring from professional rugby.
Poux is expected to complete a move to Bordeaux-Begles, while Burgess will join Australian outfit Melbourne Rebels.
