British trio Harriet Dart, Jodie Burrage and Liam Broady all suffered second-round exits at the Eastbourne International on Wednesday, leaving the host nation without any players left in the singles competitions.
Dart and Burrage came into their respective showdowns with Jelena Ostapenko and Coco Gauff as underdogs, and the latter was comprehensively beaten 1-6 1-6 by the American.
Meanwhile, Dart's run ended with a 3-6 4-6 loss to Birmingham Classic winner Ostapenko, while in the men's tournament, Broady was beaten 2-6 4-6 by Sweden's Mikael Ymer.
Burrage - runner-up to Katie Boulter at this year's Nottingham Open - earned a second bite at the cherry in Eastbourne as a lucky loser, coming from a set down to beat American Lauren Davis in round one.
However, Burrage could not replicate her feats against Davis's compatriot Gauff, who took just 59 minutes to dump the Briton out of the tournament with a merciless display.
Burrage opened with a hold to 30 before the Gauff onslaught began, as the world number seven won five games on the spin and held to love to take the first set with aplomb.
A relentless start to the second set saw Gauff storm into a 5-0 lead with a triple break, although when serving for the match, she was stunned by a Burrage break back to love.
The 24-year-old's brief fightback was futile, though, as she once again lost her serve in the seventh game on a mishit forehand, sending Gauff through to a quarter-final against Jessica Pegula.
Later in the day, Dart shared her compatriot's fate with a two-set loss to 2017 French Open winner Ostapenko, who got the job done with one hour and 31 minutes on the board.
Two missed chances to break Ostapenko proved costly for Dart in the opener, as she could not take advantage of a quintet of double faults from the Latvian and lost her serve in the eighth game.
Ostapenko saved a third break point at the start of the second set before edging ahead in a lengthy fifth game, and while she was forced to serve out the match, she comfortably sealed the deal with a ferocious forehand that Dart could only send into the net.
Meanwhile, Broady - the only British man to make the last 16 - was no match for Swedish world number 61 Ymer, despite impressively saving seven of the 11 break points he faced on the day.
However, Ymer's pressure would tell as he raced into a 4-1 lead in the opener before Broady earned one break back, but the Brit went pointless in the final two games of the first set.
The second set was a much closer affair as Broady found his first serve - remarkably landing a 100% success rate and hitting three aces - but he was broken in the seventh game before Ymer advanced with a final hold to love.
