Roger Federer believes that the home supporters will ultimately favour John Isner in their fourth-round meeting at the US Open on Monday.

The Swiss is a popular player at the US Open, but will take on a home favourite in the shape of Isner in the last 16.

Federer has said that he would be "very happy" if the crowd were on his side, but does expect his big-serving opponent to receive the most support at Flushing Meadows.

"I'm looking forward to find out. Played John here in the past. Also I think it was Labor Day weekend. Third round maybe? The crowds were really pumped up to see how massive he was clocking the serves. It was a joke in the first set. I remember that. Yeah, I expect the crowd to be on his side," Federer told reporters.

"If they are on my side, I'll clearly be very happy and appreciate that. That goes also into my preparation, to be quite honest. But I love playing here. People know that. We will see how it's going to be."

Federer has won the US Open on five separate occasions, the last of which came in 2008.