Maxime Colin will start for Brentford for the first time, after signing from Anderlecht a fortnight ago.
Philipp Hofmann continues up front for the Bees, with loan signing Marco Djuricin not registering in time to be included in the matchday squad.
Peru international Paolo Hurtado has been included in the Reading matchday squad for the first time and could make his debut from the bench.
Garath McCleary and Nick Blackman both start for Reading, after scoring during their League Cup victory over Portsmouth during the week.
Brentford: Button; Colin, Dean, Tarkowski, Bidwell; Kerschbaumer, Diagouraga; Judge, Vibe, Gogia; Hofmann
Subs: Bonham, McCormack, O'Connell, Barbet, Udumaga, Clarke
Reading: Bond; Gunter, McShane, Ferdinand, Obita; Robson-Kanu, Norwood, Quinn, Williams; Sa, Blackman.
Subs: Al-Habsi, Hector, McCleary, Hurtado, Tshibola, Fernandez, Cox
Find out Sports Mole's match prediction by watching the video below:
