Porto vs. Arsenal (Wednesday, 8.00pm)
Ending a seven-year exile from the Champions League knockout stages, Arsenal board the plane to Portugal for the first leg of their last-16 affair with Porto on Wednesday evening.
The Gunners topped Group B to set up a reunion with Sergio Conceicao's team, who sneaked into the knockout rounds via a second-placed finish in Group H behind Barcelona.
We say: Porto 1-3 Arsenal
As admirable as Porto's home defensive record is, Arsenal's astonishing attacking exploits since the turn of the year - particularly away from home - suggests that the Dragons' rearguard nous may count for little if the Gunners' offensive line is on song once again.
Porto will no doubt prove stiffer opposition than West Ham and Burnley, and the Gunners have traditionally struggled for results at the Estadio do Dragao, but we have faith in Arteta's men to capitalise on the hosts' injury problems at the back and return to North London with a healthy first-leg advantage.
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> How Arsenal could line up against Porto
> Arsenal injury, suspension list vs. Porto
Napoli vs. Barcelona (Wednesday, 8.00pm)
Two fallen giants will clash in the Champions League's last 16, as Napoli welcome Barcelona to Stadio Maradona on Wednesday evening.
Forever linked by Diego Maradona, both clubs topped their domestic leagues last season; however, neither has put up much of a title defence or impressed in the group stage.
We say: Napoli 1-2 Barcelona
While Napoli have been struggling to score; Barcelona can barely buy a clean sheet. On to their third boss of the season, the home side are as disjointed as they were united last year, so they may trail by a goal ahead of next month's return leg in Catalonia.
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