Ronald Koeman's side came up short against Real Madrid in El Clasico at the weekend, while the hosts suffered a 3-2 defeat to Real Betis, and here Sports Mole rounds up the team news for both clubs.
Out: Martin Merquelanz (knee)
Sports Mole's predicted XI: Dimitrievski; Balliu, Saveljich, Catena, F. Garcia; Lopez, Comesana; Palazon, Trejo, A. Garcia; Nteka
Doubtful: Ansu Fati (knock)
Sports Mole's predicted XI: Ter Stegen; Mingueza, Pique, Garcia, Alba; Roberto, Busquets, Gavi; Dest, Aguero, Depay