Find out how all of the action unfolded courtesy of our minute-by-minute updates below.
This is a repeat of last season's Copa del Rey final, which Valencia won to deny Barcelona the double, but there is now a new man in the dugout for the visitors after Marcelino's shock sacking during the international break. It leaves new boss Albert Celades with a tough opening task in his first match, although they face a Barcelona side still missing Lionel Messi and having only won one of their first three games this term.
Kickoff is just moments away, so let's start with a look at the team news...
SUBS: Suarez, Firpo, Todibo, Rakitic, Pena, Vidal, Roberto
SUBS: Kondogbia, Cheryshev, Costa, Lee, Domenech, Diakhaby, Gomez
It is the stuff of dreams for the starlet as he runs on to De Jong's low pass into the box, drilling his finish into the bottom corner to leave Cillessen no chance against his former club! Remember the name!
Fati is the creator on this occasion, showing great footwork and pace down the left channel to skip past Garay before pulling it back for De Jong, who blasts it home with a first-time finish!
Valencia got themselves back into it despite surrendering the lion's share of possession - and there are chances there for the visitors - but the story of the game so far has been the emergence of 16-year-old Ansu Fati.
Frenkie de Jong's low cross into the box was met by Fati, whose low first-time finish left Cillessen with no chance in the Valencia goal. Griezmann also deserves credit having let the ball run, but there was no doubting who was the man of the moment.
The experience of Garay could not nullify the skill of Fati, whose quick feet saw him skip past the defender on the left channel before pulling the ball back for De Jong to blast his finish home - a second Barcelona goal after only seven minutes.
Kevin Gameiro latched on to Rodrigo's pass before sliding his finish beyond the keeper, and while the goal was initially ruled out for offside VAR proved that he was in fact on, and allowed the goal to stand.
Cillessen will take some of the blame, though, having allowed Griezmann's low strike to squirm under his body and against the inside of the post. Pique channels his inner fox in the box to pounce on the loose ball, reacting much quicker than anyone else to tap home the rebound from close range!
This time it is Semedo who drives a low strike towards the bottom corner which is just beyond the reach of Cillessen but crashes against the inside of the post and rebounds this time to safety.
Just a minute after coming on, Suarez has his goal, and it is a really smart finish too. The Uruguayan hesitates with the ball at his feet just outside the area but then picks his spot and curls a pinpoint finish in off the foot of the near post.
The first comes at the end of the brilliant driving run forward from De Jong, who slips the ball to Griezmann. The Frenchman tries to dink his finish over the onrushing Cillessen, who stays big to make a crucial stop. The former Barca keeper then thwarts the follow-up from Perez before making a more routine save to deny Arthur moments later with Barcelona still on the attack.
Rakitic's dinked ball inside was cleared just in front of the line, but only as far as a Barcelona man. Griezmann then tees up Suarez, who again catches Cillessen out at the near post with a curling finish.
Luis Suarez came off the bench to score twice in the final half hour, but the headlines for this one will go to 16-year-old Ansu Fati, who played a starring role in the first half and had a goal and assist to his name within seven minutes.
Thank you very much for joining Sports Mole for tonight's La Liga showdown as Barcelona hit five past Valencia, with the help of their newest star Ansu Fati. I will leave you with our match report, and be sure to stick around for reaction too!
From me, though, it is goodbye for now!