There is no getting away from the fact that Barca have struggled in La Liga this term, dropping points in half of their 12 matches, suffering four defeats in the process.
The Catalan giants have picked up six points from the last six available, though, overcoming Levante last weekend before recording a huge 2-1 victory at home to Real Sociedad on Wednesday night courtesy of goals from Jordi Alba and Frenkie de Jong.
Koeman's side have moved into fifth spot in the table and are only six points behind leaders Atletico Madrid, although Diego Simeone's side also have a game in hand and therefore Barca have plenty of work to do if they are to pull themselves into a title race in the second half of the campaign.
The hosts, who will take on Paris Saint-Germain in the last-16 stage of the Champions League, will be looking to end 2020 with three straight wins over Valencia, Real Valladolid and Eibar, and a positive finish to the year would likely leave the team in a strong position in the table heading into 2021.
Barca recorded a 5-2 win over Valencia in the corresponding game last season, but they have only been victorious in one of their last four matches with Los Che in Spain's top flight.
Valencia, as mentioned, have struggled for consistency this season, picking up just 14 points from their 13 matches to sit down in 12th spot in the table ahead of the next set of fixtures.
A number of important players left Los Che over the summer, and there have been plenty of off-the-field issues this term, with head coach Javi Gracia previously admitting that he wants to leave the Mestalla and was only remaining at the club due to a contractual obligation.
Gracia's side recorded a 4-2 win over Terrassa in the first round of the Copa del Rey on Wednesday night, but they are without a victory in the league since beating Real Madrid 4-1 at home on November 8.
Only three points have arrived in their last four matches, but the six-time La Liga champions have lost just once in Spain's top flight since October 23 and are certainly capable of harming Koeman's team.
Barcelona La Liga form: WLWLWW
Barcelona form (all competitions): WWLLWW
Valencia La Liga form: DWDLDD
Valencia form (all competitions): WDLDDW
Manu Vallejo was on the scoresheet against Athletic Bilbao last weekend and should keep his spot alongside Maxi Gomez in attack, while Goncalo Guedes, Carlos Soler and Yunus Musah, who all scored off the bench in the Copa del Rey earlier this week, should return to the starting side.
Barcelona possible starting lineup:
Ter Stegen; Dest, Araujo, Lenglet, Alba; De Jong, Busquets; Braithwaite, Pedri, Griezmann; Messi
Valencia possible starting lineup:
Domenech; Wass, Paulista, Diakhaby, Gaya; Musah, Racic, Soler, Guedes; Vallejo, Gomez
We say: Barcelona 2-1 Valencia
Valencia, for all of their problems this season, are certainly capable of pulling off a surprise win at Camp Nou. Barca's win over Sociedad was extremely important, though, and will have left the hosts in a confident mood ahead of this contest; we are expecting a tight affair but expect Koeman's side to triumph.