Pedro has failed to retain his place in the Barcelona starting lineup against Real Sociedad despite his performance on Saturday.
The Spain international attacker scored a hat-trick against Rayo Vallecano away from home in La Liga, but Alexis Sanchez has been preferred to him this evening.
Neymar continues to start for the defending Spanish champions for tonight's La Liga match, while Javier Mascherano plays in central defence. Cesc Fabregas is not in the Barca squad.
Meanwhile, Sociedad have Carlos Vela and Chory Castro on the bench, while Antoine Griezmann starts.
Barcelona: Valdes; Alves, Pique, Mascherano, Adriano; Xavi, Iniesta, Busquets; Sanchez, Messi, Neymar
Real Sociedad: Bravo; Estrada, Cadamuro, Martinez, De la Bella; Bergara, Ros, Prieto, Sangalli; Seferovic, Griezmann
