Barnsley have decided to start veteran goalkeeper Mike Pollitt who was recently drafted in on loan from Wigan Athletic, with regular number one goalkeeper Luke Steele left on the bench.
New striker Marcus Pedersen, a season-long loanee from Dutch side Vitesse Arnhem, also makes his first league start for the club having previously featured in Barnsley's 5-1 Capital One Cup defeat to Southampton.
Huddersfield Town have left out defender Calum Woods, despite the full-back being rumoured to have recovered from a knock in time to feature at Oakwell. In-form striker James Vaughan starts up top.
Barnsley: Pollitt; Kennedy, Wiseman, Mvoto, O'Brien, Dawson, Perkins, Etuhu, Noble-Lazarus, O'Grady, Pedersen
Huddersfield Town: Smithies; Lynch, Gerrard, Clarke; Carroll, Norwood, Clayton, Hogg, Hammill; Scannell, Vaughan