French media have reported that record signing Emiliano Sala was on board the plane travelling from Nantes to Cardiff that went missing.
French media, quoting police sources, said Sala was on the light aircraft that disappeared from radar on Monday night while apparently flying from Nantes to Cardiff.
Cardiff chief executive Ken Choo has given an interview to the club's media department that is expected to be released later this afternoon.
The Premier League club cancelled their scheduled training session on Tuesday morning, which Sala had been due to take part in.
The 28-year-old Argentinian striker completed a move to the Premier League club over the weekend but had returned to France, where he had been playing for Ligue 1 side Nantes.
France's civil aviation authority said Sala was aboard the plane, according to reports.
Cardiff chairman Mehmet Dalman told the Mirror: "We are very concerned by the latest news that a light aircraft lost contact over the Channel last night.
"We are awaiting confirmation before we can say anything further. We are very concerned for the safety of Emiliano Sala."
Sala had signed a three-and-a-half year deal with the Welsh club after scoring 12 Ligue 1 goals in 19 appearances this season.