Napoli vs. Genk (Tuesday, 5.55pm)
The Italian outfit only need a point to confirm their place in the last 16 of the competition, while Genk are already certain to finish bottom of Group E.
We say: Napoli 2-0 Genk
Napoli cannot seem to buy a win at the moment, but it is hard to see anything other than a home victory in this match. Genk have a dreadful record in the Champions League, particularly away from home, and look like ideal opposition for Napoli as they bid to end a nine-game winless run.
Salzburg vs. Liverpool (Tuesday, 5.55pm)
It is all to play for when Red Bull Salzburg welcome Liverpool to the Red Bull Arena on Tuesday night, with both sides knowing that victory could seal their place in the last 16 of the Champions League.
Holders Liverpool lead the way in Group E heading into the final matchday and only need to avoid defeat to progress, but a win for Salzburg would likely see them leapfrog the European champions via the head-to-head rule.
We say: Salzburg 2-3 Liverpool
Salzburg games almost guarantee goals, and with Liverpool far from convincing at the back so far this season this could be a high-scoring affair. There is some top-class attacking talent on show and ultimately we are backing the reigning champions to have the experience and knowhow to get the result they need to secure top spot.
Ajax vs. Valencia (Tuesday, 8pm)
We say: Ajax 1-1 Valencia
We fancy Ajax to get the point that they need to book their spot in the next round, and it will then be a case of wait and see for Valencia as they hope for a favour from Lille against Chelsea.
Benfica vs. Zenit St Petersburg (Tuesday, 8pm)
We say: Benfica 1-2 Zenit Saint Petersburg
The combination of a five-game winning run and the importance of this fixture, compared with Benfica's lowly performances in Europe over the last few years, puts Sergei Semak's side in the box seat to take all three points in this game.
Borussia Dortmund vs. Slavia Prague (Tuesday, 8pm)
However, Slavia make the trip to the Westfalenstadion unable to move off bottom spot in Group E, despite having secured draws away at Barcelona and Inter earlier in the campaign.
We say: Borussia Dortmund 3-1 Slavia Prague
While Dortmund have not always been at their best on the domestic front this season, we are backing them to deliver an important win here. Slavia have shown in recent months that they are capable of claiming a result on away territory, although we feel that Dortmund have too much firepower in the final third.
Chelsea vs. Lille (Tuesday, 8pm)
Chelsea head into Tuesday night's Champions League meeting with Lille knowing that victory is required in order to reach the knockout stages.
Meanwhile, after failing to win any of their five matches, Lille make the trip to Stamford Bridge having already finished in bottom spot in Group H.
We say: Chelsea 2-1 Lille
Given Chelsea's recent inconsistent form, this could prove to be a cagey affair. However, while their struggles at the back could give Lille something to work with, we feel that the Premier League outfit will grind out an important win.
Inter Milan vs. Barcelona (Tuesday, 8pm)
Inter Milan will be looking to join Barcelona in the last-16 stage of the Champions League when both teams round off their Group F campaign with a clash in Italy on Tuesday night.
Barca have already booked their spot in the knockout round as group winners, but Inter are battling Borussia Dortmund for the second qualification spot.
We say: Inter Milan 1-1 Barcelona
It would not be a surprise if Inter triumphed on Tuesday night, but a Barca victory would also not be a shock due to their recent form. We are finding it difficult to separate them, though, and fancy Inter to pick up a point which might well be enough to book their spot in the knockout round of the competition.
Lyon vs. RB Leipzig (Tuesday, 8pm)
The visitors are already guaranteed to qualify, while Lyon must better the result of Zenit Saint Petersburg, who are level on points with the French side but have the superior head to head record.
We say: Lyon 1-1 RB Leipzig
In a hotly-contested game between two relatively even teams, you suspect that neither team will be able to convincingly pull ahead of the other.
Lyon will throw everything at this game, but Leipzig are a highly dangerous team who will no doubt put the Ligue 1 side into some awkward positions defensively.
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