Captain John Terry and midfielder Frank Lampard will start Chelsea's Champions League fixture in Genk on the bench.
Fernando Torres comes into the starting lineup in place of the injured Didier Drogba, with Nicolas Anelka playing alongside him up front.
Former Portsmouth defender Anthony Vanden Borre will play at full-back for Racing Genk, while reported Chelsea transfer target Kevin De Bruyne also starts.
Genk: Koteles; Vanden Borre, Nadson, Hyland, Anele; Buffel, Camus, Tozser, De Bruyne, Vossen; Kennedy
Chelsea: Cech; Bosingwa, Luiz, Ivanovic, Cole; Romeu, Meireles, Ramires, Malouda; Anelka, Torres