Enzo Maresca has opted to use Levi Colwill as a replacement for the suspended Marc Cucurella for Sunday's Premier League game at Everton.
The Spaniard is serving a one-match ban for picking up a second yellow card after the full-time whistle of last weekend's win over Brentford.
With Renato Veiga having deputised in the past, the expectation had been that the young Portugal international would step in at left-back.
Instead, Colwill has been moved to full-back with Tosin Adarabioyo and Axel Disasi getting the nod in the centre.
With Romeo Lavia failing to overcome a minor injury, Moises Caicedo and Enzo Fernandez continue in the centre of the pitch.
That effectively left Maresca with just a decision to make regarding his wingers, the Italian taking the choice to use Pedro Neto and Jadon Sancho with Noni Madueke being selected on the substitutes' bench.
Everton stay with team from Arsenal draw
Meanwhile, Sean Dyche has opted against making any alterations to the Everton XI that earned a goalless draw at Arsenal last time out.
With the likes of James Garner and Dwight McNeil remaining unavailable, the Toffees XI effectively picked itself on the back of their performance at the Emirates Stadium.
Everton XI: Pickford; Young, Tarkowski, Branthwaite, Mykolenko; Gueye, Mangala; Harrison, Ndiaye, Doucoure; Calvert-Lewin
Subs: Virginia, Patterson, Keane, Beto, O'Brien, Chermiti, Coleman, Lindstrom, Armstrong
Chelsea XI: Sanchez; Gusto, Tosin, Disasi, Colwill; Caicedo, Fernandez; Neto, Palmer, Sancho; Jackson
Subs: Jorgensen, Acheampong, Veiga, Rak-Sakyi, Dewsbury-Hall, George, Joao Felix, Nkunku, Guiu
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