Kai Havertz has been given the nod over Pierre-Emerick Aubameyang for Chelsea's Premier League fixture at Brighton & Hove Albion.
Havertz netted a stunning winning goal against Red Bull Salzburg in the Champions League in midweek, while Aubameyang squandered a number of opportunities.
As a result, the Gabon international has dropped down to the substitutes' bench, leaving Havertz to lead the line with Mason Mount in support.
On his first return to the Amex Stadium signing joining Chelsea last month, Graham Potter has made minimal changes, seemingly sticking with Christian Pulisic and Raheem Sterling at wing-back.
The only other alteration comes in central midfield with Jorginho, who played 90 minutes in Austria, being replaced by Ruben Loftus-Cheek.
With Carney Chukwuemeka not selected in the squad, former Arsenal youngster Omari Hutchinson has been included on the substitutes' bench.
Brighton & Hove Albion: Sanchez; Webster, Dunk, Estupinan; March, Mac Allister, Caicedo, Trossard; Gross, Mitoma; Lallana
Subs: Steele, Lamptey, Sarmiento, Enciso, Undav, Gilmour, Turns, Furlong, Moran
Chelsea: Arrizabalaga; Chalobah, Silva, Cucurella; Pulisic, Gallagher, Kovacic, Loftus-Cheek, Sterling; Mount; Havertz
Subs: Mendy, Azpilicueta, Chilwell, Jorginho, Zakaria, Hutchinson, Ziyech, Aubameyang, Broja