Georgia vs. Kosovo (Thursday, 5.00pm)
The bottom two nations in UEFA World Cup Qualifying Group B convene on Thursday, as Georgia host pointless Kosovo in Batumi.
Both looking for a first win of the process, the pair are outsiders in a challenging section also containing Spain, Sweden and Greece.
We say: Georgia 2-1 Kosovo
Both sides are desperate to get a victory under their belt this week, but home advantage should help Georgia edge out a Kosovo team comprising some talented ball-players by a fine margin.
Though passage to the World Cup remains a pipe dream, the two nations are capable of some progressive football and have pushed better-resourced teams close - so an entertaining match could be in prospect.
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Italy vs. Bulgaria (Thursday, 7.45pm)
European champions Italy return to the World Cup qualifying trail on Thursday, as they welcome Bulgaria to Florence's Stadio Artemio Franchi.
After a triumphant summer which changed perceptions of them around the globe, the Azzurri look to continue their perfect start to the qualification process for Qatar 2022.
We say: Italy 2-0 Bulgaria
As Bulgaria's goal threat is minimal, even if the Azzurri cannot hit the heights of midsummer, they should comfortably record another two-goal win to keep their 100% record intact before the weekend clash with Switzerland.
Roberto Mancini has a wealth of attacking talent at his disposal and they will be eager to continue in the same vein until they reach Qatar next winter.
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> How Italy could line up against Bulgaria
Lithuania vs. N. Ireland (Thursday, 7.45pm)
Northern Ireland travel to Lithuania for the third game of their World Cup 2022 qualification campaign at the LFF Stadium on Thursday evening.
The sides sit third and fifth respectively in Group C, some way off the top two of Italy and Switzerland, but Northern Ireland will stand a good chance of claiming a first win here.
We say: Lithuania 0-1 Northern Ireland
It may be tight but Northern Ireland really should have enough to earn a first victory of the campaign against a Lithuania side at a low ebb, who are also missing their captain.
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Czech Republic vs. Belarus (Thursday, 7.45pm)
Czech Republic welcome Belarus to the Mestsky Stadion on Thursday evening for the fourth match of their World Cup Qualifying campaign in Group E.
The hosts are aiming to qualify for their first World Cup since 2006, while the visitors have never competed in a major tournament since securing independence in 1991.
We say: Czech Republic 2-0 Belarus
Belarus will be aiming to frustrate the Czech Republic on Thursday, but if they defend anything like the way they did against Belgium then the hosts should have no problems in claiming all three points.
Despite the absence of Patrik Schick in attack, the Czechs still have enough quality in the final third to secure a routine win on home soil.
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Estonia vs. Belgium (Thursday, 7.45pm)
Top meets bottom in World Cup 2022 Group E qualifying on Thursday night, as Estonia welcome leaders Belgium to the Lillekula Stadium in Tallinn.
The hosts are rooted to the bottom of the pile after losing their first two games, while Belgium have taken seven points from a possible nine so far.
We say: Estonia 0-5 Belgium
Estonia's Baltic Cup triumph has at least given Haberli's side something to build on before a taxing week in September, but their momentum will surely come to a grinding halt against the top-ranked nation in the world.
With Belgium aiming to lay down a marker following another missed opportunity to lift an international trophy, a romping success should follow for the Red Devils.
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Andorra vs. San Marino (Thursday, 7.45pm)
European minnows Andorra and San Marino lock horns on Thursday evening for the fourth match of their World Cup Qualifying campaign in Group I.
The two nations, currently ranked outside of the world's top 150, will be looking to avoid finishing bottom of their group for the very first time in their history.
We say: Andorra 1-0 San Marino
Andorra and San Marino have rarely headed into any fixture with real belief that they can claim a victory, though Thursday's match is certainly one that provides both nations with confidence of securing all three points.
A closely-fought contest is set to be played out at the Estadi Nacional, with few goals to be expected, but we can see the hosts securing a narrow win on home soil.
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Hungary vs. England (Thursday, 7.45pm)
Having come so close yet so far at Euro 2020, the England squad reunite for September's World Cup 2022 Qualifying clashes, starting with Thursday's trip to the Puskas Arena to take on Hungary.
The Three Lions have taken maximum points from their opening three games in qualification Group I, while Hungary sit second in the group with two wins and a draw so far.
We say: Hungary 1-2 England
Hungary proved throughout Euro 2020 that they are no pushovers, and the chance to leapfrog England at the top of the group means that Rossi's men will be reluctant to shy away from goalscoring opportunities.
We would not put it past the hosts to make the net ripple on their own turf, but England's added attacking quality should shine through during a narrow but crucial success.
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> How England could line up against Hungary
> 5 talking points ahead of England's World Cup qualifier with Hungary
Poland vs. Albania (Thursday, 7.45pm)
An indifferent start to the process sees Poland with ground to make up in Group I of the World Cup qualifiers, when they welcome Albania to Warsaw on Thursday.
The Euro 2020 finalists were only able to beat minnows Andorra during their first three matches of the campaign, while their visitors already have six points on the board.
We say: Poland 2-1 Albania
Lewandowski's return to the qualifying campaign provides a major plus for Poland ahead of the resumption, but Albania are a serious proposition under a wily and revered head coach - with plenty of Serie A experience also available amongst his personnel.
The visitors are set to push the Poles all the way, but a stark difference in quality within the width of the goalposts should decide a close-run encounter in the home side's favour.
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Iceland vs. Romania (Thursday, 7.45pm)
Both Iceland and Romania will be looking for their second win of Group J when they meet on Thursday at the Laugardalsvollur in the latest World Cup 2022 qualifying game.
The visitors head into the game on a four-game losing run, while the hosts shall be hoping to extend their undefeated streak to three games with a positive result.
We say: Iceland 1-1 Romania
Both teams are in a desperate need of three points within this qualification group, but with neither being in particularly great form it is more likely that they will both be cautious.
Because of that, a draw is something that could take place here with each squad hoping to build on that in the group games that follow within this international break.
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Liechtenstein vs. Germany (Thursday, 7.45pm)
Germany start a new era in the unassuming surrounds of St. Gallen on Thursday, as they continue their quest to reach the next World Cup under new management.
A Nationalmannschaft selected by Hansi Flick will travel to meet Liechtenstein on Swiss soil, aiming to recover from a rocky start to European Qualifying Group J and another deflating major tournament performance.
We say: Liechtenstein 0-6 Germany
Only the group winners qualify automatically for the finals, so Germany will be eager to get back on track in style under their new manager, who prefers a front-foot approach.
This is the third meeting between the Nationalelf and little Liechtenstein - following 4-0 and 6-0 wins for the former in 2010 World Cup qualifying - and, if selected, their top-class forwards will ensure a similar result this time around.
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> How Germany could line up against Liechtenstein
N. Macedonia vs. Armenia (Thursday, 7.45pm)
North Macedonia will continue their charge for a place in the 2022 World Cup finals when they take on Armenia at Philip II Arena on Thursday.
Following their unsuccessful showing at Euro 2020, North Macedonia will be seeking some form of redemption with a positive result in this World Cup qualifying fixture.
We say: North Macedonia 2-1 Armenia
Macedonia are very strong on home turf, having remained unbeaten in their last nine matches, and will be confident of keeping this impressive run going here.
The visitors are in the form of their lives at the moment and should give the hosts a difficult time, but Risovi's home advantage should be enough to help them to victory come full time.
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Sweden vs. Spain (Thursday, 7.45pm)
Sweden and Spain will both return to international action on Thursday, when they square off in World Cup Qualifying action.
The two nations have both had strong starts to qualification, while they also come into the upcoming round of fixtures on the back of relatively impressive showings at Euro 2020 in the summer, as the visitors narrowly missed out in the semi-finals.
We say: Sweden 1-1 Spain
Sweden will certainly be no pushovers on Thursday, and given their impressive quality and Spain's weakened squad, we do not see La Roja winning on their travels.
We are instead opting for a draw that should be relatively pleasing for both nations, as they look to keep hold of the top spots in the qualifying group.
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> How Spain could line up against Sweden body check tags ::