With his side 4-0 up after the first leg against Ponferradina, Getafe coach Luis Garcia Plaza has chosen to name an inexperienced side for the second leg.
Hugo Fraile and Adrian Colunga are handed their first Getafe starts of the season up front alongside the more familiar face of Diego Castro.
Young goalkeeper Jordi Codina makes his second appearance of the season while Miguel Torres shores up an inexperienced defence at right-back.
Getafe: Codina; Torres, Mane, Michel, Sarabia; Borja, Lacen, Gavilan; Castro, Fraile, Colunga
Ponferradina: Quintana; Robuste, Rodriguez, Samu, Vera; Baro, Lafuente, Jonathan, Cortes; Moreno; Albis