Bayer Leverkusen manager Sami Hypia has made three changes to his side to face Hamburger SV in an effort to shore up his defence.
Following last week's 3-2 defeat at Hannover the manager has dropped Manuel Friedrich, Daniel Carvajal and Stefan Reinartz.
Omer Toprak, Sebastian Boesnich and Jens Hegler all come in to start for the Bundesliga's second-placed side.
Hamburg have stuck with an adventurous side for the trip to the Bay Arena, naming Artjoms Rudnevs and Son Heung-Min in a two-man attack.
Leverkusen: Leno, Hosogai, Wollscheid, Toprak, Boenisch, Hegeler, Rolfes, Bender, Schürrle, Castro, Kiessling
Hamburg: Adler, Diekmeier, Mancienne, Westermann, Lam, Skjelbred, Badelj, Arslan, Aogo, Sun, Rudnevs
