Torino vs. Spezia (Saturday, 2.00pm)
Separated by seven points in the standings - with Ivan Juric's men holding the upper hand - the teams meet with safety assured, despite indifferent results of late.
We say: Torino 1-1 Spezia
Pitching together two of the lowest-scoring teams outside the bottom three, this fixture is surely bound for a close-fought draw.
Even though Spezia are the team to have faced the most shots in Serie A this season, timid Torino have landed only a league-low 97 on target themselves, so a goalfest is not on the cards.
Venezia vs. Atalanta (Saturday, 2.00pm)
The teams convene at Stadio Pier Luigi Penzo for the first time in the top flight since March 2002, with both searching for an end to worrying winless streaks.
We say: Venezia 0-1 Atalanta BC
Both teams have been short of ideas in the final third over recent weeks, and that promises a low-scoring affair by the lagoon.
More effective on their travels throughout the campaign, Atalanta can finally eke out a win and start to rebuild their confidence ahead of Serie A's final furlong.
Inter Milan vs. Roma (Saturday, 5.00pm)
Though Inter - who reached the Coppa Italia final in midweek with a Milan Derby win - would return to the summit with their fifth successive victory, the Giallorossi kept their unbeaten run going with a late equaliser at Napoli last time out and are sprinting towards the finish line.
We say: Inter Milan 1-1 Roma
Roma are the Serie A side with the most different players to have scored at least twice this term (12) - closely followed by Inter (11) - but Tammy Abraham remains their greatest threat to the champions.
They have also been more sure-footed defensively in recent weeks, with fit-again Chris Smalling to the fore, so Mourinho can throw a spanner in the works by restricting his old employers to a point.
Hellas Verona vs. Sampdoria (Saturday, 7.45pm)
The teams meet at Stadio Bentegodi with the home side revelling in an away victory over Atalanta, while Samp slumped to defeat against rock-bottom Salernitana and are yet to assure their safety.
We say: Hellas Verona 2-1 Sampdoria
None of Sampdoria's last 14 league games have ended level - and most have ended in defeat - so a draw is overdue for the visitors.
However, Verona are particularly prolific on their own patch, and fielding a more fluent front line than their opponents can help them to another home victory.