Having both been shocked by Costa Rica and beaten England, Italy and Uruguay will meet in Natal's Estadio das Dunas for the right to advance through to the knockout stages of the World Cup on Monday.
The draw will favour the Italians, who have a better goal difference than their Uruguayan counterparts.
Cesare Prandelli left Marco Verratti out of his starting lineup for the clash with Costa Rica, but the Paris Saint-Germain midfielder could return. There have been further suggestions that Ciro Immobile may feature up front, but the Borussia Dortmund frontman could well start among the substitutes again.
As for Uruguay, they will have Maximiliano Pereira available for selection following suspension, but Alvaro Pereira may miss out because of concussion. Captain Diego Lugano is also unlikely to feature because of a knee complaint.
These two nations have met on eight previous occasions, with Italy winning the head to head record 3-2. Their most recent encounter came at last year's Confederations Cup, when after a 2-2 draw, the Azzurri won 3-2 on penalties.
Recent form
Italy: LDDWWL
Uruguay: DDWWLW
Possible starting lineups
Italy: Buffon; Abate, Barzagli, Chiellini, Darmian; De Rossi, Pirlo, Verratti, Marchisio, Candreva; Balotelli
Uruguay: Muslera; A Pereira, Gimenez, Godin, Caceres; M Pereira, Gargano, Rodriguez, Arevalo; Suarez, Cavani
Sports Mole says: 0-1