Juventus vs. Torino (Saturday, 4.15pm)
Juventus will be looking for their seventh straight victory in Serie A when they welcome Turin rivals Torino to the Allianz Stadium on Saturday afternoon.
The Old Lady currently sit four points clear of second-placed Lazio at the top of the table, while Torino occupy 14th, six points clear of the relegation zone in Italy's top flight.
We say: Juventus 2-0 Torino
Torino are certainly capable of making it a difficult afternoon for the champions, but it is tough to back against Juve due to their excellent form. We fancy a relatively routine home victory, which would move Sarri's side seven points clear at the summit before second-placed Lazio take on Milan.
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> How Juventus could line up against Torino
Sassuolo vs. Lecce (Saturday, 6.30pm)
Lecce will be looking to end a run of five straight Serie A defeats and boost their survival hopes in the process when they travel to Sassuolo on Saturday night.
The visitors are currently 18th in the table, one point behind 17th-placed Genoa, while Sassuolo occupy 12th position and recorded an impressive 3-1 win at Fiorentina on Wednesday night.
We say: Sassuolo 2-0 Lecce
Lecce's recent form is extremely poor, but Sassuolo will enter the match off the back of a fine result. The home side have a lot of talent in the final third of the field, and we fancy them to pick up all three points here.
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Lazio vs. AC Milan (Saturday, 8.45pm)
Lazio's pursuit of Serie A leaders Juventus will continue on Saturday night when they welcome top-six hopefuls AC Milan to the Stadio Olimpico for what should be an enthralling clash.
The home side are currently second in the table, four points behind leaders Juventus, while Milan sit seventh, two points behind sixth-placed Napoli, who have a game in hand.
We say: Lazio 2-1 AC Milan
The fact that Lazio are missing their leading scorer is a huge boost for Milan, who will be determined to record their 13th league victory of the season. It would not be a surprise to see the two sides share the points, but we just fancy Lazio to sneak a victory despite their absentees.