Lorik Cana's last-gasp equaliser five minutes into stoppage time has helped Lazio salvage a point at Sampdoria, denying Sinisa Mihajlovic a dream start to life in Genoa.
Mihajlovic made wholesale changes for his first game in the Samp hotseat and got an immediate response, with Pedro Obiang and Manolo Gabbiadini threatening early on.
Positive early signs were soon forgotten after the interval, though, with Nenad Kristicic sent off for a second bookable offence just moments into the second half.
Lazio used their numerical advantage to threaten as Bryan Perea struck the post, but the Aquile fell behind to 10-man Samp midway through the second period.
Roberto Soriano was the man who broke the deadlock, powering home a header from close range.
The hosts were unable to hang on for all three points, though, as a wave of late Lazio pressure told deep into injury time, with Cana pouncing on a Sergio Floccari flick to scramble home a dramatic equaliser.