The 28-year-old had an outside chance of taking part at the Brentford Community Stadium after taking part in training this week following a spell out with a foot injury.
However, the Whites will be without the striker due to a positive COVID-19 test and he will join Stuart Dallas, Adam Forshaw and Crysencio Summerville on the sidelines, while Daniel James and Luke Ayling are both suspended.
A back four of Robin Koch, Liam Cooper, Diego Llorente and Junior Firpo will protect Illan Meslier between the sticks, while Kalvin Phillips will operate in centre-midfield behind attacking quintent Greenwood, Rodrigo, Raphinha, Jack Harrison and Joe Gelhardt.
Leeds need to better Burnley's result at home against Newcastle United if they are to avoid relegation to the Championship. body check tags ::