The Foxes are five points clear of fifth-placed Chelsea in the battle for a top-four finish, while opponents Burnley are five points above the relegation zone after going three games without a win.
Here, Sports Mole rounds up all of the latest team news for both sides.
Sports Mole's predicted XI: Pope; Lowton, Tarkowski, Mee, Taylor; Brownhill, Westwood, Stephens, McNeil; Wood, Rodriguez
Out: Harvey Barnes (knee), Ayoze Perez (knee), Dennis Praet (thigh), James Justin (knee), Wes Morgan (back)
Doubtful: James Maddison (hip), Wesley Fofana (thigh), Jamie Vardy (calf), Jonny Evans (calf)
Sports Mole's predicted XI: Schmeichel; Castagne, Evans, Soyuncu, Thomas; Ndidi, Tielemans; Pereira, Under, Albrighton; Vardy
Watch the Sports Mole Football Shorts prediction for this game below: