SM
| Venue: St. Mary's Stadium |
Southampton | ||
| D | 35 | Jan Bednarek |
| D | 3 | Ryan Manning |
| D | 2 | Kyle Walker-Peters |
| D | 21 | Taylor Harwood-Bellis |
| M | 17 | Stuart Armstrong |
| M | 7 | Joe Aribo |
| A | 36 | David Brooks |
| M | 4 | Flynn Downes |
| A | 9 | Adam Armstrong |
| A | 10 | Che Adams |
| G | 1 | Alex McCarthy |
Preston North End | ||
| G | 1 | Freddie Woodman |
| D | 16 | Andrew Hughes |
| M | 26 | Jack Whatmough |
| D | 6 | Liam Lindsay |
| D | 14 | Jordan Storey |
| M | 11 | Robbie Brady |
| M | 25 | Duane Holmes |
| A | 10 | Mads Frøkjær-Jensen |
| M | 35 | Noah Mawene |
| A | 19 | Emil Riis Jacobsen |
| A | 28 | Milutin Osmajić |
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