The Reds, who memorably stunned Barcelona 4-0 at Anfield having lost the first leg of their 2019 semi-final 3-0 at the Nou Camp, have another tough task on their hands this year after going down 3-1 in the Spanish capital last week.
Wednesday’s match also takes place five years to the day since they pulled off an added-time victory to beat Klopp’s former side Borussia Dortmund in a Europa League quarter-final second leg, having been 4-2 down on aggregate with 24 minutes to go.
But Klopp knows his players were a shadow of themselves in the Estadio Alfredo Di Stefano at Real’s training complex and expects to see a difference this time around.
“When you are 3-1 down, it looks like we are already out. It means we have not a lot to lose so we will give it a try – that’s the job we have to do,” he said.
“The idea is to win the game (on Wednesday night). If that will end up in a comeback I have no idea, but I never had before.
“We have to bring ourselves in a mood and we start believing in that again. If we can see it is possible then we have a chance but it is still incredibly difficult.”