Raphael Varane and Alvaro Arbeloa will both reportedly come into the Real Madrid defence for Tuesday's Champions League fixture against Liverpool.
Los Blancos' first-choice back four this season has consisted of Dani Carvajal, Pepe, Sergio Ramos and Marcelo.
However, with Pepe expected to be rested and Carvajal out of action with a hamstring problem, head coach Carlo Ancelotti will make two changes to his side.
Gareth Bale has returned to training following a hip problem, but the Welshman is not expected to be involved from the start at the Bernabeu.
