Real Madrid could potentially be without Toni Kroos, Eden Hazard, Federico Valverde and Dani Carvajal for next week's Champions League quarter-final against Liverpool.
All four individuals were absent from training on Wednesday through different injuries which could rule them out for next Tuesday's first leg at the Santiago Bernabeu.
Hazard, who has only registered four goals and seven assists in 36 appearances since joining the Spanish giants in July 2019, will miss the tie after suffering with a series of injury problems this season.
It is very likely that the Belgium international will be joined by right-back Carvajal in the stands for both legs due to a hamstring problem for the Spaniard.
Real Madrid will be more hopeful about Valverde and Kroos for at least one leg but will have to assess both individuals, with the former recovering from muscular problems and the German midfielder sustaining an abductor problem during the international break.
Before hosting Liverpool, Los Blancos play in La Liga against Eibar on Saturday.