Tottenham will be without Harry Kane and Moussa Sissoko against Liverpool.
Kane (hamstring) and Sissoko (knee) are both out until April following surgery on their respective injuries.
Danny Rose (calf) is back in training but Ben Davies (ankle), Hugo Lloris (elbow) and Tanguy Ndombele (hip) miss out.
Liverpool's James Milner is set to miss at least the next two matches with a hamstring injury.
Fellow midfielder Naby Keita (groin) also remains unavailable for the next fortnight but centre-back Joel Matip, out since October with a knee injury, and Xherdan Shaqiri trained this week.
Longer-term absentees Fabinho, out since late November also with a knee injury, and Dejan Lovren (hamstring) are set to come back next week.
Tottenham provisional squad: Gazzaniga, Vorm, Aurier, Walker-Peters, Foyth, Sanchez, Alderweireld, Vertonghen, Rose, Sessegnon, Skipp, Dier, Wanyama, Winks, Lamela, Lo Celso, Alli, Eriksen, Son, Moura, Parrott.
Liverpool provisional squad: Alisson, Alexander-Arnold, Van Dijk, Gomez, Robertson, Henderson, Wijnaldum, Oxlade-Chamberlain, Salah, Firmino, Mane, Adrian, Williams, Matip, Lallana, Jones, Shaqiri, Origi.