Atletico vs. Feyenoord (Wednesday, 5.45pm)
Denied by a dramatic last-gasp equaliser on the opening day, Atletico Madrid aim for their first Champions League Group E win on Wednesday, when Feyenoord arrive in the Spanish capital.
While Atleti have won all three of their league matches since coming up just short against Lazio, their Dutch counterparts followed victory over Celtic by extending their own success streak to six games.
We say: Atletico Madrid 2-1 Feyenoord
As Atletico Madrid have won just one of their last 11 home matches in the Champions League - drawing on no less than seven occasions - something must change soon or they risk a second straight group exit. With fearless Feyenoord lacking their star striker due to suspension, a window of opportunity now presents itself, so Simeone's men can edge to victory by the odd goal in three.
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Antwerp vs. Shakhtar (Wednesday, 5.45pm)
An early basement battle in Champions League Group H takes place at the Bosuilstadion on Wednesday, as Royal Antwerp meet Shakhtar Donetsk in matchweek two.
The hosts were crushed 5-0 by Barcelona on the opening matchday, while their Ukrainian counterparts were no match for Porto, going down 3-1 in Hamburg.
We say: Royal Antwerp 0-1 Shakhtar Donetsk
Even Antwerp's recent streak of impressive defensive displays should count for little against a Shakhtar side who always find a way through the opposition's defence, even if they come out on the wrong end of the scoreline, as was the case a fortnight ago.
However, with several key players set to return to the XI against a Reds side lacking attacking inspiration, Shakhtar need only prolong their prolific streak in front of goal to emerge victorious and leave Antwerp still searching for their first group-stage point.
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Celtic vs. Lazio (Wednesday, 8.00pm)
Having experienced contrasting fortunes on the Champions League's opening matchday, Celtic and Lazio convene at Celtic Park on Wednesday, with both seeking a first Group E success.
While the Scottish champions imploded during the second half of their defeat to Feyenoord, last season's Serie A runners-up snatched a point against Atletico Madrid in the most dramatic style.
We say: Celtic 1-2 Lazio
Winless in their last 11 meetings with British sides in UEFA competition - a run dating back to March 2000 - Lazio should end that drought with victory in Glasgow this week. Although the Biancocelesti are struggling to replicate last season's form, Celtic have been unconvincing in Europe for some time now and have some key defensive absentees.
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Dortmund vs. AC Milan (Wednesday, 8.00pm)
Both searching for their first Champions League Group F win at the second attempt, Borussia Dortmund and AC Milan pit their wits against one another at the Signal Iduna Park on Wednesday.
Edin Terzic's men fell to a 2-0 defeat to Paris Saint-Germain on matchday one, while the Rossoneri were left to rue a string of wasted chances in a 0-0 draw with Newcastle United.
We say: Borussia Dortmund 1-0 AC Milan
Unbeaten on home soil since August 2022, Dortmund can prolong their hot streak at Signal Iduna Park against a depleted Milan team, whose midfield options are severely limited at the minute.
The Rossoneri already struggle for prolific attacking displays in the Champions League, and while making the net ripple domestically is never normally an issue for Pioli's team, their powers should wane against a Dortmund side who possess plenty of defensive wherewithal in front of the home crowd.
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Newcastle vs. PSG (Wednesday, 8.00pm)
The French champions visit St James' Park for a tantalising Champions League Group F tie on Wednesday evening, as Newcastle United play host to Paris Saint-Germain.
Eddie Howe's men marked their return to the big time with a hard-fought goalless stalemate away to AC Milan on matchday one, while Les Parisiens saw off Borussia Dortmund 2-0.
We say: Newcastle United 1-2 Paris Saint-Germain
Both Newcastle and PSG have displayed admirable defensive resilience over the past few weeks, but the Magpies in particular should fear no foe after seeing off Man City - albeit a weakened Man City - in front of their own fans just a week ago.
The boisterous St James' Park atmosphere will also play its part in intimidating the French champions, but despite the visitors' stretch of inconsistent form, keeping Mbappe and co quiet might be a step too far for an injury-ravaged Magpies team.
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> How Newcastle could line up against PSG
RB Leipzig vs. Man City (Wednesday, 8.00pm)
Champions League holders Manchester City will be looking to bounce back from successive domestic defeats when they travel to Germany for a group-stage clash with RB Leipzig on Wednesday night.
The Citizens and Die Roten Bullen currently sit joint top of Group G after beating Red Star Belgrade and Young Boys respectively by a 3-1 scoreline in their opening fixture two weeks ago.
We say: RB Leipzig 1-2 Manchester City
Man City may have breezed to victory in their last meeting with Leipzig, but a much closer affair is set to be in store on Wednesday considering the contrasting form of the two teams.
Leipzig will fancy their chances of breaching City's backline, but the expected return of Rodri is a huge boost for the visitors, who we believe will bounce back from their recent setbacks to claim maximum points, especially if Haaland laces up his shooting boots.
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> How Man City could line up against RB Leipzig
> Man City injury, suspension list vs. RB Leipzig
Red Star vs. Young Boys (Wednesday, 8.00pm)
Red Star Belgrade and Young Boys will be looking to record their first win in Group G of the Champions League when they do battle at the Rajko Mitic Stadium on Wednesday night.
The hosts were beaten 3-1 away against holders Manchester City in their opening group game two weeks ago, while the visitors lost to RB Leipzig by the same scoreline.
We say: Red Star Belgrade 1-1 Young Boys
Red Star, who have won one of their three home games in both of their previous two Champions League group appearances, will view Wednesday's fixture as their best opportunity to open their account in Group G.
The same can be said for Young Boys, though, and with little to separate these two teams, a closely-fought score draw could be played out in Serbia.
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Porto vs. Barcelona (Wednesday, 8.00pm)
Both on the hunt for back-to-back wins in Champions League Group H, Porto and Barcelona prepare for battle at the Estadio do Dragao on Wednesday evening.
Sergio Conceicao's side put Shakhtar Donetsk to the sword 3-1 in their continental opener, while the Spanish champions produced a five-star performance to destroy Royal Antwerp.
We say: Porto 1-3 Barcelona
Porto's stellar home feats coupled with Barcelona's struggles for Champions League successes away from their Catalan headquarters could make Wednesday's affair a trickier one than it would appear on paper for Xavi's side, but the visitors' attacking qualities should soon come to the fore.
Alongside their injury-hit defence, Porto's morale would have taken a hit with their painful loss to Benfica at the weekend, and we have faith in Barcelona to make it two wins from two in Group H.
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