The Citizens, who remain second in the table, had been due to face Arsenal on Wednesday night but concerns over the coronavirus outbreak saw the top-flight fixture postponed.
Here, Sports Mole looks at how City could line up against the Clarets this weekend.
> Click here for Man City's latest injury and suspension news ahead of this match
City were without both Kevin De Bruyne and Aymeric Laporte at Old Trafford due to shoulder and hamstring injuries respectively, but the pair are expected to be ready for this weekend's contest.
Sergio Aguero should also overcome the thigh problem that he picked up against Man United, although Guardiola could make changes in attack with Gabriel Jesus potentially coming into the side.
Riyad Mahrez, Kyle Walker, Benjamin Mendy and David Silva are also in line for recalls, meaning that the likes of Bernardo Silva, Joao Cancelo, Ilkay Gundogan and Alexander Zinchenko could all drop out.
Leroy Sane continues to make progress in his recovery from a knee operation, but the Germany international will not be considered for the clash with Sean Dyche's side.