Victory for Manchester United during tomorrow's trip to CFR Cluj would be their 100th in the Champions League.
If they are to reach that milestone against the Romanians, they will have to do so without the services of Ryan Giggs, Paul Scholes, Antonio Valencia and Michael Carrick.
Manager Sir Alex Ferguson has decided to leave the quartet at home in order to rest up ahead of the weekend's trip to Newcastle United.
Youngster Scott Wootton may feature after he was handed a squad number, while Darren Fletcher is also expected to be included.
Hosting Cluj will be without Ciprian Deac, Adam Vass, Bakary Sare and Ronny, all of whom are suffering with injuries.
However, Vasile Maftei is available following the completion of his one-match suspension.
This will be the first time that these two clubs have met competitively.
Recent form
Cluj: WWWWWW
Man United: LWWWWW
Possible lineups:
Cluj: Felguerias; Pinto, Cadu, Rada, Sepsi; Muresan, Alberto, Sougou, Bastos, Camora; Kapetanos
Man United: De Gea; Rafael, Evans, Wootton, Buttner; Fletcher, Anderson, Cleverley, Welbeck; Hernandez, Rooney
Sports Mole says: 1-2