West Ham vs. Arsenal (Wednesday, 7.30pm)
Seeking to inflict a fourth successive defeat on their London rivals, Arsenal make the short journey across the capital to meet West Ham United in Wednesday's EFL Cup fourth-round tie.
Both sides emerged 1-0 victors from their third-round affairs, as the Irons sneaked past Lincoln City, while Mikel Arteta's troops narrowly overcame Brentford.
We say: West Ham United 0-2 Arsenal
Having finally been stunted on home soil, West Ham are fighting an uphill battle to regain their golden touch against an Arsenal backline who have proven an extremely tough nut to crack more often than not on the road this term.
A raft of rotations from both managers means that neither capital outfit may be at their best, but barring any April-esque capitulations, Arteta's charges ought to make the most of West Ham's dip in form to stroll into the quarter-finals.
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> How Arsenal could line up against West Ham
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Ipswich vs. Fulham (Wednesday, 7.45pm)
Having already sent one Premier League team packing in this year's EFL Cup, high-flying Ipswich Town seek to add Fulham to their list of victims when they meet at Portman Road in Wednesday's fourth-round contest.
The Tractor Boys eliminated Wolverhampton Wanderers with a stunning 3-2 win in the third round, while the Cottagers got the job done against Norwich City in a 2-1 triumph.
We say: Ipswich Town 2-2 Fulham (Fulham to win on penalties)
With six wins to show from their last six contests at Portman Road - scoring at least three goals in each of those eye-catching wins - Ipswich have nothing to fear on Wednesday, although their defensive vulnerabilities will open the door to Fulham's attackers.
Ninety minutes may not be enough to settle this intriguing battle, which may have to be decided from the dreaded 12-yard mark, and just as they did against Tottenham, Fulham's esteemed players should utilise their big-game experience to end the Tractor Boys' dreams of glory.
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Bournemouth vs. Liverpool (Wednesday, 7.45pm)
Having finally got off the mark in the Premier League at the 10th attempt, Bournemouth will endeavour to pull off a significant EFL Cup scalp when Liverpool head to the Vitality Stadium for Wednesday's fourth-round showdown.
The Cherries eased past Stoke City 2-0 in their previous knockout affair, while the Reds came from behind to record a 3-1 win - as has been tradition this season - over Leicester City.
We say: Bournemouth 1-3 Liverpool
Boosted by a timely injection of confidence, Bournemouth ought to play without fear in a contest where few will expect them to come out on top, which might spell danger for a Liverpool backline that remains far from impermeable.
Klopp will certainly not be afraid to shuffle his pack, but with an enviable selection of in-form attackers bound to begin the contest, the Reds should still prove too hot for the Cherries to handle.
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> How Liverpool could line up against Bournemouth
> Liverpool injury, suspension list vs. Bournemouth
Chelsea vs. Blackburn (Wednesday, 7.45pm)
Five-time EFL Cup winners Chelsea welcome Championship side Blackburn Rovers to Stamford Bridge for a fourth round clash on Wednesday.
After a promising set of results, Chelsea were left reeling by another damaging defeat at the weekend which has seen them drop back into the Premier League's bottom half.
We say: Chelsea 2-0 Blackburn Rovers
Despite their woes so far this season, Chelsea's record against lower-league opposition speaks for itself and they should progress here.
Blackburn will fancy their chances given their goalscoring exploits in this competition so far, and the form of Chelsea, but a huge upset may be just beyond them.
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> How Chelsea could line up against Blackburn
> Chelsea injury, suspension list vs. Blackburn
Everton vs. Burnley (Wednesday, 7.45pm)
Premier League outfits Everton and Burnley face off for a place in the EFL Cup quarter-finals at Goodison Park on Wednesday night as Sean Dyche faces his former club for the first time since being sacked in 2022.
The Everton faithful are desperate to see their side end a current 28-year run without a trophy, and a win at Aston Villa in the last round has put them in a great position to potentially have a run in this competition.
We say: Everton 1-1 Burnley (Everton to win on penalties)
Everton's form at home has been worrying this season while all of Burnley's results have come on the road, including two away wins in the previous two rounds.
Despite the contrast of emotions from over the weekend, this could be a close contest, with both sides set to rotate many players, and it could well go the distance.
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Man Utd vs. Newcastle (Wednesday, 8.15pm)
Only one of last year's EFL Cup finalists can enter the pot for the 2023-24 quarter-final draw, as Manchester United renew hostilities with Newcastle United in Wednesday's fourth-round battle at Old Trafford.
Erik ten Hag's men put three past Crystal Palace without reply to cruise into the last 16, while the Magpies ended Manchester City's quadruple hopes with a memorable one-goal triumph.
We say: Manchester United 1-1 Newcastle United (Newcastle to win on penalties)
Something is just not clicking with Man United's expensively-assembled attacking contingent at the moment, and not even the introduction of a few fresh legs should help to solve Ten Hag's conundrum in all areas of the field.
Newcastle's poor away record does at least offer the Red Devils some hope of keeping their grip on the trophy, and 90 minutes may not be enough to settle a repeat of the 2022-23 final, but we can envisage the Magpies holding their nerve from 12 yards to eliminate the holders and prolong the Red Devils' distress.
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> How Man United could line up against Newcastle
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