Brighton vs. Chelsea (Wednesday, 12.30pm)
Chelsea make the trip to the Amex Stadium to face Brighton & Hove Albion on New Year's Day looking to strengthen their grip on fourth position in the Premier League standings.
Meanwhile, the Seagulls head into the contest having moved five points clear of the relegation zone courtesy of a 2-0 triumph over Bournemouth at the weekend.
We say: Brighton & Hove Albion 2-2 Chelsea
This has all the makings of an entertaining tussle, with Brighton strong in front of their own supporters and Chelsea remaining unpredictable, regardless of whether they are playing home or away. We feel that there is every chance of this contest ending level after a late goal.
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> How Chelsea could line up against Brighton
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Burnley vs. Aston Villa (Wednesday, 12.30pm)
Burnley play host to Aston Villa in the Premier League on New Year's Day looking to avoid a third successive defeat over the current hectic period.
As for Villa, they make the trip to Turf Moor sitting in the relegation zone, one point away from safety.
We say: Burnley 3-1 Aston Villa
While Villa will feel that they have to right the wrongs of their most recent performances, they do not match up well against Dyche's hard-working side. On that basis, the home side could run out comfortable winners in the North-West.
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Newcastle vs. Leicester (Wednesday, 3pm)
Newcastle United host Leicester City at St James' Park in their first match of 2020, with both clubs having enjoyed better-than-expected campaigns so far.
The Magpies sit 11th in the table after 20 games - closer to fifth than they are to the relegation zone - whereas Leicester are flying high in second place, albeit 13 points adrift of leaders Liverpool.
We say: Newcastle 1-2 Leicester
Newcastle have generally been good in front of their own fans this season, but with a lengthy injury list and Leicester back towards full strength this looks like a tough test for them. It will not be easy for the Foxes either, but we are backing them to complete the double over the Magpies.
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Southampton vs. Tottenham (Wednesday, 3pm)
Tottenham Hotspur begin the new decade with a trip to St Mary's as Southampton welcome Spurs to the south coast on New Year's Day.
Jose Mourinho's side sit sixth in the table and five points off the Champions League spots ahead of their visit to a resurgent Southampton, who eased their relegation concerns during a much-improved December.
We say: Southampton 2-2 Tottenham
Goals should be guaranteed in this match considering how much both teams have struggled to keep clean sheets, particularly at home for Southampton and away for Spurs. These two sides have picked up exactly the same number of points over the past seven games and we can see them cancelling each other out here.
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> How Tottenham could line up against Southampton
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Watford vs. Wolves (Wednesday, 3pm)
Wolverhampton Wanderers face Watford at Vicarage Road on New Year's Day less than 72 hours after narrowly losing out to leaders Liverpool at Anfield.
As for the Hornets, they have had an extra day's rest on the back of comfortably overcoming relegation rivals Aston Villa at the weekend.
We say: Watford 2-1 Wolverhampton Wanderers
While Wolves have impressed against the two biggest clubs in the division, we feel that their efforts in those games will take its toll here. Watford have, so far, been excellent under Pearson, and we are backing the home side to secure another crucial victory.
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Man City vs. Everton (Wednesday, 5.30pm)
Everton will be looking to continue their 100% start under Carlo Ancelotti when they travel to champions Manchester City on New Year's Day.
The Toffees have beaten Burnley and Newcastle United in their two matches since Ancelotti took control, while City will enter the clash off the back of a 2-0 win over Sheffield United.
We say: Manchester City 2-1 Everton
Everton are certainly capable of making it a very uncomfortable 90 minutes for City, but we are finding it difficult to back against a win for the champions. We fancy De Bruyne to find the back of the net in a 2-1 home success.
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> How Man City could line up against Everton
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Norwich vs. Crystal Palace (Wednesday, 5.30pm)
Norwich City will be looking for just their fourth Premier League win of the 2019-20 campaign when they welcome Crystal Palace to Carrow Road on New Year's Day.
The Canaries will enter 2020 bottom of the table on 13 points, while Palace sit ninth having collected 27 points from their first 20 league matches of the 2019-20 campaign.
We say: Norwich City 1-1 Crystal Palace
Norwich put a lot into their clash with Tottenham on Saturday, but it is difficult to back an away win with any real confidence considering Palace's injury problems. We fancy a low-scoring draw at Carrow Road, which would not be the worst result in the world for either side.
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West Ham vs. Bournemouth (Wednesday, 5.30pm)
David Moyes will take charge of his first match in his second spell as West Ham United boss on New Year's Day as the Hammers prepare to welcome Bournemouth to the London Stadium.
Manuel Pellegrini was sacked by West Ham following the 2-1 home defeat to Leicester City on Saturday, and Moyes will be hoping for the perfect start against fellow strugglers Bournemouth on Wednesday.
We say: West Ham United 2-1 Bournemouth
It is difficult to call this match a relegation six-pointer, but there is no getting away from the fact that it is a huge clash for both teams. Bournemouth are capable of harming the Hammers, but we expect the hosts to shade an extremely close match at the London Stadium.
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Arsenal vs. Man Utd (Wednesday, 8pm)
The New Year gets underway in style on Thursday as Arsenal and Manchester United renew hostilities with the latest chapter in arguably the most enduring and defining rivalry of the Premier League era.
Far from the peak of the 1990s and early 2000s, though, both sides enter the new decade sitting outside the top four and looking to rediscover their past glories under the leadership of a former player.
We say: Arsenal 2-2 Man Utd
These high-profile showdowns can often be difficult to call, and this one especially so with both sides being dogged by inconsistency this season. The form book and league table points to a United win, but Arsenal have not got what they deserved from Arteta's two matches at the helm so far and we are backing them to come away with at least a point from this one.
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> How Arsenal could line up against Man Utd
> How Man Utd could line up against Arsenal
> Click here for Arsenal's latest injury and suspension news ahead of this match
> Click here for Man Utd's latest injury and suspension news ahead of this match
> Combined XI: Arsenal vs. Manchester United
Liverpool vs. Sheffield United (Thursday, 8pm)
Two of the Premier League's standout performers during the first half of the season meet on Friday when runaway leaders Liverpool host high-flying Sheffield United at Anfield.
Jurgen Klopp's side begin 2020 with a commanding 13-point lead at the top of the table, while Sheffield United have surpassed all expectations to sit eighth after 20 games, 11 points clear of the relegation zone.
We say: Liverpool 2-0 Sheffield United
Sheffield United are likely to pose serious questions of Liverpool just as they did in the reverse fixture, but the Reds look unstoppable at the moment, particularly at Anfield.
It is by no means a banker for the champions elect and could be exactly the type of fixture which sees them drop points at the tail end of such a hectic schedule, but it is hard to back anything other than a Liverpool win at the moment.
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> How Liverpool could line up against Sheffield United
> Click here for Liverpool's latest injury and suspension news ahead of this match