Manchester United will be without Casemiro for their clash with Leicester City at Old Trafford on Sunday, as the Brazilian serves the last game of his three-match suspension.
Casemiro was given a straight red card for violent conduct against Crystal Palace at the start of the month and missed their two matches with Leeds United last week.
He did feature in the Europa League against Barcelona on Thursday, and will be available for selection next weekend when they face Newcastle United in the EFL Cup final at Wembley.
That could mean that Marcel Sabitzer gets a third consecutive start in his absence since arriving on loan from Bayern Munich on deadline day.
Midfield is where most of United's injury problems lie, as Christian Eriksen and Donny van de Beek are both out long term, while Scott McTominay remains a big doubt for this one.
That leaves Fred as their only other available senior central midfielder, so he should start alongside Sabitzer in the middle.
Erik ten Hag changed his defence around for the trip to Leeds United last weekend, giving Harry Maguire a rare start, as Raphael Varane and Lisandro Martinez were left on the bench.
Ten Hag could opt to do something similar again with the return leg of their Europa League tie with Barcelona coming up on Thursday.
In attack, Antony and Anthony Martial are both unlikely to feature here, as the duo recover from minor injuries, so Jadon Sancho could start again after showing some promising signs on his return from a lengthy layoff.
Marcus Rashford has become undroppable at the moment for United, as he continues his knack of scoring vitally important goals.
He scored their first goal in both league clashes with Leeds which helped them on their way to collecting four points, while also having a big impact at Camp Nou on Thursday, scoring and assisting as they came from behind before eventually drawing 2-2.
Manchester United possible starting lineup:
De Gea; Dalot, Varane, Martinez, Shaw; Sabitzer, Fred, Fernandes; Sancho, Weghorst, Rashford
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