Everton vs. Man Utd (Saturday, 12.30pm)
Merseyside meets Manchester on Saturday lunchtime as Everton welcome Manchester United to Goodison Park with both sides seeking a return to winning ways after back-to-back defeats.
The Toffees have seen their bright start to the campaign tail off in recent weeks, while Man United are languishing in 15th place following their joint-worst start to a campaign since 1986-87.
We say: Everton 2-2 Manchester United
Both of these sides are struggling for form heading into this match, and Man United's hugely underwhelming start to the campaign will no doubt lead many to regard Everton as favourites.
Ancelotti's side have tailed off themselves in recent weeks, though, making it tough to pick a winner in this one. We can see goals, but we expect the spoils to be shared on Merseyside.
Our tipster partners are predicting an away win.
> Click here to read our full preview for this match
> How Man United could line up against Everton
> Man Utd injury, suspension list vs. Everton
> A look at Man United's previous poor starts ahead of Everton clash
Crystal Palace vs. Leeds (Saturday, 3.00pm)
Crystal Palace and Leeds United will both be looking to bounce back from respective defeats when the two sides meet at Selhurst Park for Saturday's Premier League showdown.
Palace suffered a 2-0 defeat away to Wolverhampton Wanderers last time out, whereas Leeds were no match for Leicester City at Elland Road on Monday.
We say: Crystal Palace 2-2 Leeds United
The Eagles will feel confident of getting back amongst the goals against a leaky Leeds defence, but the Whites have produced some good showings on the road and Palace have several absentees to contend with themselves. Zaha and Bamford will be key to either side's chances of taking all three points, and while both teams are sure to be gunning for glory at Selhurst Park, we are ultimately backing a high-scoring draw.
Our tipster partners are predicting an away win.
> Click here to read our full preview for this match
Chelsea vs. Sheff Utd (Saturday, 5.30pm)
In-form Chelsea could move to within one point of Premier League leaders Liverpool when they welcome struggling Sheffield United to Stamford Bridge on Saturday afternoon.
Frank Lampard's men have put their defensive issues behind them after a shaky start to the campaign, and host a Sheffield United side still with only one point to their name this season.
We say: Chelsea 2-0 Sheffield United
It is increasingly hard to back Sheffield United in any game at the moment, yet alone away to a Chelsea side really beginning to find their feet after such heavy summer investment.
The Blades do not lose by big scorelines in general and will no doubt make Chelsea work for the points, but the hosts should have more than enough to pile more misery onto Sheffield United's shoulders.
Our tipster partners are predicting a home win.
> Click here to read our full preview for this match
> How Chelsea could line up against Sheffield United
> Chelsea injury, suspension list vs. Sheffield United
West Ham vs. Fulham (Saturday, 8.00pm)
West Ham United will endeavour to bounce back from their narrow defeat to Liverpool when they welcome Fulham to the London Stadium for Saturday's derby in the Premier League.
In contrast, Scott Parker's men finally managed to register a win in the top flight as they overcame West Bromwich Albion 2-0 on Monday night.
We say: West Ham United 2-1 Fulham
Having finally managed to register a Premier League win at the seventh attempt in the 2020-21 campaign, Fulham will be aware that their trip to the London Stadium represents possibly their best chance of another triumph for the next month or so. However, West Ham have performed valiantly over the past few weeks and are sure to feel confident of returning to winning ways here, so we are backing Moyes's men to come out on top in the capital.
Our tipster partners are predicting a home win.