One of the defining rivalries of the Premier League era enters its latest chapter on Saturday afternoon when Arsenal welcome Manchester United to the Emirates Stadium.
Seven places and 10 points separate the two sides in the table, but it is ninth-placed Arsenal who go into the game off the back of a victory while second-placed Manchester United were left reeling by defeat to Sheffield United last time out.
Match preview
Showdowns between these two once-great rivals may not be what they used to be when they went a long way towards deciding the destination of the Premier League title, but they still carry an extra edge.
Two former players who know all about the history of this fixture are now in the dugouts, and they will no doubt be demanding that the current crop do their predecessors justice.
Man United boss Ole Gunnar Solskjaer will be demanding an immediate reaction from his side after they slumped to a 2-1 home defeat at the hands of Sheffield United on Wednesday night, but for Arsenal's Mikel Arteta the message will be to continue where they left off last time out.
The Gunners swiftly avenged their FA Cup exit at the hands of Southampton by beating them in the Premier League, again at St Mary's, just three days later, with talented teenager Bukayo Saka further enhancing his burgeoning reputation with another goal and assist.
That result lifted Arsenal up to ninth in the standings and continued a resurgence which has catapulted them up towards the top of the form table, with only Manchester City having picked up more points over the last six games.
The scale of the turnaround has been stark; Arsenal have picked up 16 points from the last 18 on offer, more than doubling both their points tally and their goal tally in the process.
Arteta's men won just four of their first 14 league games this season but have now won five of their last six, while they netted 12 goals in those opening 14 games - whereas the last six outings have yielded 16 goals.
Of course, sitting ninth in the table after 20 games is still a disappointing return for Arsenal, but they at least appear to now be back on the right track, with a growing identity to go with their improving results.
Certainly, the pressure on Arteta's shoulders has eased, and both he and his counterpart in this match Solskjaer will be thankful to their clubs for keeping faith in a position where Chelsea did not with Frank Lampard.
In addition to an improvement going forward, inspired by Saka and ably assisted by Alexandre Lacazette's return to form, Arsenal have also been better defensively, with only Southampton having scored against them in their last seven outings across all competitions.
At home, Arsenal have kept three clean sheets in a row - as many as they had managed in their previous 19 games at the Emirates - and Saturday offers them the opportunity to extend that to four on the bounce for the first time since April 2019 - a run which, incidentally, included victory over Manchester United.
There could also be a small slice of history on offer for Arteta as he looks to become the first ever Arsenal boss to win each of his first three league games against Man United, while that is a feat only three managers of any club have ever achieved in the Premier League era.
Such a result would be another dent in the title hopes which have grown at Man United this season, but the Red Devils are chasing history themselves as they travel to North London.
A win or a draw would see Solskjaer's side make it 18 consecutive top-flight away games unbeaten stretching back more than a year, something Man United have never managed before in their illustrious history.
The 20-time English champions have won more points and scored more goals away from home than any other Premier League side this season, so a trip to an Arsenal team with a distinctly average home record should not faze them.
However, their confidence will have no doubt taken a hit during their 2-1 defeat to bottom-of-the-table Sheffield United in midweek, as the Blades upset all the odds to deal a reality check to the title hopefuls.
Whereas Man United's away form has been peerless so far, the loss to Sheffield United was their fourth at home already this term - their most in a single season since the David Moyes campaign of 2013-14.
The Red Devils' uncanny habit of coming from behind to win - something they have achieved seven times already this season - abandoned them on Wednesday, denying them the chance to regain top spot from local rivals Manchester City.
The result also ended a 13-match unbeaten streak in the Premier League, which incidentally stretched back to the reverse of this fixture, which Arsenal won 1-0 at Old Trafford on November 1.
Pierre-Emerick Aubameyang settled that game from the penalty spot, but Man United have not lost back-to-back league games for more than a year now and will know that a repeat of that result on Saturday would put the title race firmly into the hands of an ominous-looking Man City.
Arsenal Premier League form: WWWDWW
Arsenal form (all competitions): WWDWLW
Manchester United Premier League form: WWWDWL
Manchester United form (all competitions): WWDWWL
Team News
Arteta has offered hope that club captain Aubameyang could return for this game, having missed the last two matches due to his mother being unwell.
The 31-year-old's situation is very much up in the air, but if available he is expected to go straight back into the starting XI, having scored in four of his last five games against Man United.
Indeed, having netted the only goal of the game in the reverse fixture, Aubameyang could become only the second player to score the winner in both top-flight matches for Arsenal against Man United, emulating Jimmy Brain from 1925-26.
Thomas Partey and Emile Smith Rowe both came off with minor muscle complaints against Southampton and will be assessed ahead of kickoff for this one, while new signing Martin Odegaard is available but may not be thrown straight into the starting lineup having only recently arrived.
Kieran Tierney is also a doubt due to a leg injury, while this match will likely come too soon for Dani Ceballos and Pablo Mari, both of whom are expected back in training in the next few days.
Man United will check on the fitness of Eric Bailly, who was due to face Sheffield United but was forced to withdraw after picking up a knock in training.
The injury is not thought to be serious, but the quick turnaround in fixtures is likely to see him miss out to Victor Lindelof, who was an unused substitute in midweek.
The likes of Luke Shaw, Fred and Scott McTominay will be pushing for inclusion once again, while Edinson Cavani will hope to lead the line after Anthony Martial came in for criticism for his performance on Wednesday.
All of Cavani's first four Premier League goals have come away from Old Trafford - the first Man United player to have done that - while behind him the usually-reliable Bruno Fernandes has now gone four league games without a goal or an assist.
Arsenal possible starting lineup:
Leno; Bellerin, Holding, Luiz, Cedric; Thomas, Xhaka; Saka, Smith Rowe, Pepe; Lacazette
Manchester United possible starting lineup:
De Gea; Wan-Bissaka, Lindelof, Maguire, Shaw; Fred, McTominay; Rashford, Fernandes, Pogba; Cavani
Head To Head
Manchester United have not won a league game against Arsenal since April 2018, including all four meetings under Solskjaer, who is the only Man United manager to have faced the Gunners more than once in the top flight without winning.
Three of those four meetings have ended in defeat, including each of the last two, and another Arsenal victory on Saturday would see them make it three on the bounce for the first time since September 1998, in addition to completing a Premier League double over the Red Devils for only the fourth time.
Arsenal could also record three consecutive home league wins over their old rivals for the first time since May 1991, having won the corresponding fixture last season 2-0.
We say: Arsenal 1-1 Manchester United
Man United's defeat to Sheffield United makes this contest even more difficult to call; on the one hand Solskjaer will expect a response from his side, but on the other it was exactly the type of result which caused some to exercise caution over declaring them genuine title contenders.
We could learn a lot about United's true credentials in this match against an in-form Arsenal side which will be full of confidence as they attempt to rectify their appalling start to the season.
Man United's away record is far superior to Arsenal's home record this term and that is difficult to ignore, but in the end we can see these two sides sharing the spoils on Saturday.
Top betting tip
Video prediction
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