Two teams who produced responses to disappointing results at the weekend meet in the Premier League on Wednesday as Manchester United visit Newcastle United.
The Red Devils saw their seven-match unbeaten run ended by Swansea City last Saturday, but bounced back to comfortably beat Sunderland 2-0 at Old Trafford.
Captain Wayne Rooney scored both of the goals to ensure that he did not go a career-worst nine Premier League games without finding the net.
The result kept United in the top four and games against Tottenham Hotspur and Liverpool later this month could go a long way to deciding their Champions League fate.
FA Cup glory is also on United's agenda, but with their blockbuster quarter-final against Arsenal not until Monday, Louis van Gaal is unlikely to rest players for the trip to Tyneside.
With Michael Carrick, Robin van Persie and Phil Jones all still sidelined, the Dutchman may not deter too far from the side which earned United a fourth win in six outings.
Luke Shaw, who was left out against the Black Cats due to tiredness, could return at left-back in the only change, with Marcos Rojo shifting inside to a more familiar central role.
Rooney has been pushed further forward in recent weeks after a long spell in midfield and is expected to play just in behind Radamel Falcao, whose Old Trafford career is believed to be reaching make-or-break time.
Reports this week claimed that the Colombian striker's agent will meet with United officials this week to discuss the likelihood of his loan move from Monaco being converted into a big-money permanent deal come the summer.
One man whose United future already appears uncertain is Juan Mata, who has not started for the club in over a month. The Spanish playmaker, Marouane Fellaini and Adnan Januzaj may all have to settle for places on the bench.
Newcastle's humiliation was worse than a narrow defeat in Wales as they were flattened 5-0 by Manchester City. John Carver demanded a response and got one as his side ground out a 1-0 victory over Aston Villa on Saturday.
Papiss Cisse's strike was the difference between the sides, and the Magpies might have found themselves in relegation trouble had it not been for his 11 goals this season, which have come at the best minutes-to-goal ratio in the league.
As it is, Newcastle are safely positioned in 11th in the table, although somewhat in limbo, with five points back to Alan Pardew's Crystal Palace in 12th and four points separating them and the top half of the table.
Who they can get on the field may dictate in which direction the remainder of their campaign goes, with Siem de Jong, Cheick Tiote, Remy Cabella, Paul Dummett and Steven Taylor still injured, and Jack Colback suspended.
Massadio Haidara is also a doubt after picking up an injury against Villa, with Ryan Taylor on standby to fill in at left-back. Ayoze Perez is poised for a recall after his rest and should replace Emmanuel Riviere in attack.
The Red Devils have won by an aggregate of 7-0 on their last two visits to St James' Park.
Newcastle:
Form in Premier League: WWDWLW
Possible starting lineup: Krul; Janmaat, Coloccini, Williamson, Taylor; Abeid, Sissoko; Ameobi, Perez, Obertan; Cisse
Man United:
Form in Premier League: WWDWLW
Form in all competitions: WDWWLW
Possible starting lineup: De Gea; Valencia, Smalling, Rojo, Shaw; Blind, Herrera; Young, Rooney, Di Maria; Falcao
Sports Mole says: 0-2