David Moyes has handed Shinji Kagawa a Premier League start as Manchester United welcome West Bromwich Albion to Old Trafford this afternoon.
The United boss has also recalled Anderson in midfield, who will play alongside Michael Carrick in the centre of the park.
Wayne Rooney starts in attack with midweek hero Javier Hernandez, while Robin van Persie is on the bench.
West Brom manager Steve Clarke has retained the services of new signing Stephane Sessegnon, who scored in his first start last weekend.
The Albion boss has also decided to go with Morgan Amalfitano in midfield following the player's impressive performance last weekend.
Manchester United: De Gea; Jones, Ferdinand, Evans, Buttner, Nani, Carrick, Anderson, Kagawa, Rooney, Hernandez
West Bromwich Albion: Myhill; Jones, McAuley, Olsson, Ridgewell, Yacob, Mulumbu, Amalfitano, Sessegnon, Sinclair, Anichebe