Chelsea defender David Luiz has been dropped by manager Antonio Conte as Manchester United travel to Stamford Bridge.
Luiz featured in Chelsea's 3-0 humbling in Rome in midweek but Thomas Christensen has been preferred by Conte at centre-back.
In midfield, N'Golo Kante makes a return to the starting line-up alongside Cesc Fabregas, while Alvaro Morata starts up front.
Manchester United manager Jose Mourinho selects the same side that defeated Tottenham Hotspur at Old Trafford last weekend.
Eric Bailly, Phil Jones and Chris Smalling are the three centre-backs as both Romelu Lukaku and Marcus Rashford start in attack.
Chelsea: Courtois; Azpilicueta, Christensen, Cahill; Zappacosta, Bakayoko, Kante, Fabregas, Alonso; Hazard, Morata
Subs: Caballero, Rudiger, Ampadu, Drinkwater, Willian, Pedro, Batshuayi
Manchester United: De Gea; Bailly, Jones, Smalling; Valencia, Herrera, Matic, Young, Mkhitaryan; Lukaku, Rashford
Subs: Romero, Blind, Darmian, Fellaini, McTominay, Lingard, Martial
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