Erik ten Hag has made four changes to his Manchester United XI for Tuesday's Premier League fixture against Aston Villa.
On the back of losing to West Ham United at the weekend, Ten Hag is under increasing pressure to turn things around, and that has led to a number of notable alterations.
Scott McTominay and Antony have each been dropped after the defeat at the London Stadium, while youngster Willy Kambwala is selected on the substitutes' bench and Luke Shaw is not named in the squad.
Raphael Varane has recovered from illness to feature in the centre of defence, while Diogo Dalot will deputise at left-back.
Christian Eriksen is handed a start in the midfield, with Marcus Rashford being given his first opportunity in the first XI since the defeat at Newcastle United on December 2.
Meanwhile, Unai Emery has made two alterations from the Villa starting lineup that begun the draw with Sheffield United on Friday.
Matty Cash misses out through suspension after collecting his fifth yellow card of the season, while Moussa Diaby is named among the replacements.
Diego Carlos is restored to the team with Ezri Konsa moving to right-back, and Leander Dendoncker is provided with his first Premier League start of the campaign in central midfield.
Manchester United: Onana; Wan-Bissaka, Varane, Evans, Dalot; Mainoo, Eriksen; Rashford, Fernandes, Garnacho; Hojlund
Subs: Bayinder, Reguilon, Kambwala, Gore, Hannibal, McTominay, Van de Beek, Pellistri, Antony
Aston Villa: Martinez; Konsa, Carlos, Lenglet, Digne; McGinn, Dendoncker, Luiz, J. Ramsey; Bailey; Watkins
Subs: Marschall, Proctor, Torres, Moreno, Chambers, Diaby, Zaniolo, Duran, Iroegbunam