The late heart-breaker was a blow with three matches of the season remaining, but Matic knows United cannot afford to wallow in self-pity.
"Of course (we have) the semi-final of the FA Cup against Chelsea, so we will give our best to make our supporters proud.
"Of course, three months ago it was not in our hands everything.
"We had to play, we had to wait for Chelsea and Leicester to drop points, which they did obviously.
"Now we are one point to Chelsea and it's in our hands. We'll take it game by game. We think about Palace first.
"Then if we do our job there, like we normally are doing, so I am not afraid that we will (not) play Champions League next season."
As for Southampton, the last-gasp draw extended their impressive unbeaten run to a fourth successive Premier League match.
Obafemi maintained that form with his goal off the bench – a memorable moment for the 20-year forward.
"It was an amazing performance from the boys and a great point away from home, even though we wanted to get all three," the Republic of Ireland international said.
"It's amazing to get the equaliser, it's what I'm here to do.
"I'm happy to have gotten on and helped the team, which will give us a big boost for the upcoming games.
"There was an Under-18s Youth Cup match I was supposed to play here, but I got ill with chicken pox.
"I've come here today and got my goal, and that's what I wanted to get here so I'm thankful I've done that."