With painful memories of last season's 4-0 Gtech Community Stadium crushing, Manchester United head south to reunite with a struggling Brentford side on Saturday evening.
The Red Devils entered the international break nine places and 21 points better off than Thomas Frank's men in the table, and here Sports Mole rounds up the team news for both clubs.
BRENTFORD vs. MANCHESTER UNITED
BRENTFORD
Out: Sergio Reguilon (suspended), Kevin Schade (groin), Ben Mee (ankle), Rico Henry (knee), Josh Dasilva (knee), Aaron Hickey (thigh), Christian Norgaard (back), Ethan Pinnock (ankle)
Doubtful: None
Sports Mole's predicted XI: Flekken; Zanka, Collins, Ajer; Roerslev, Janelt, Onyeka, Jensen, Lewis-Potter; Mbeumo, Toney
MANCHESTER UNITED
Out: Amad Diallo (suspended), Luke Shaw (muscle), Anthony Martial (groin), Tyrell Malacia (knee)
Doubtful: Harry Maguire (unspecified), Casemiro (knock), Altay Bayindir (strain), Jonny Evans (unspecified), Lisandro Martinez (knee)
Sports Mole's predicted XI: Onana; Wan-Bissaka, Lindelof, Varane, Dalot; Mainoo, McTominay; Garnacho, Fernandes, Rashford; Hojlund
For data analysis of the most likely results, scorelines and more for this match please click here.