Konstantinos Mitroglou will lead the line for Marseille in Thursday night's Europa League semi-final first leg against Red Bull Salzburg.
The Greece striker is picked in the starting XI ahead of ex-Monaco forward Valere Germain, who is named on the bench.
Meanwhile, former Newcastle United man Florian Thauvin and ex-West Ham United attacker Dimitri Payet will provide support alongside Lucas Ocampos.
Rolando hobbled off in the win over Lille last time out with an Achilles problem and is only fit enough for a place on the bench, with Luiz Gustavo dropping into the backline alongside Adil Rami.
Bouna Sarr deputises for Japan international Hiroki Sakai, who is out with a knee injury and is in a race against time to be fit again before the campaign comes to an end.
As for Salzburg, 19-year-old Hannes Wolf comes in for Xaver Schlager in central midfield, lining up alongside Diadie Samassekou, who is back from suspension.
Moanes Dabbur, the Austrian Bundesliga's top scorer this term, continues his strike partnership with youngster Hwang Hee-chan.
Marseille: Pele; Amavi, Gustavo, Rami, Sarr; Sanson, Lopez; Ocampos, Payet, Thauvin; Mitroglou
Subs: Bedimo, Escales, Germain, Njie, Rolando, Sertic, Anguissa
Red Bull Salzburg: Walke; Ulmer, Caleta-Car, Ramalho, Lainer; Berisha, Samassekou, Haidara; Wolf; Dabbur, Hwang
Subs: Stankovic, Onguene, Pongracic, Yabo, Minamino, Schlager, Gulbrandsen
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