Grant Leadbitter and Lee Tomlin have both been named in the Middlesbrough side for the meeting with Millwall at the Riverside Stadium.
Both players were used as substitutes in the 2-0 defeat to Sheffield Wednesday at the weekend, but they return in midfield as Dean Whitehead and Adam Forshaw drop to the bench.
There is no place in the squad for Kenneth Omeruo or James Husband as Aitor Karanka hands starts to Ryan Fredericks and George Friend.
Ian Holloway has named an unchanged Millwall side as Lee Gregory leads the line once again with support from Gary Taylor-Fletcher.
Middlesbrough: Konstantopoulos, Fredericks, Kalas, Gibson, Friend, Leadbitter(c), Clayton, Adomah, Tomlin, Bamford, Kike
Millwall: Forde, Abdou, Dunne, Hooiveld, Harding, Tonge, Williams, Woolford, Fabbrini, Taylor-Fletcher, Gregory